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文献标题：
Longitudinal in vivo reproducibility of cartilage volume and surface in osteoarthritis of the knee.
参考中文标题：
纵向重复性体内的软骨体积和表面膝关节骨性关节炎的。
文献摘要：
OBJECTIVE: The aim of this study was to evaluate the longitudinal reproducibility of cartilage volume and surface area measurements in moderate osteoarthritis (OA) of the knee. MATERIALS AND METHODS: We analysed 5 MRI (GE 1.5T, sagittal 3D SPGR) data sets of patients with osteoarthritis (OA) of the knee (Kellgren Lawrence grade I-II). Two scans were performed: one baseline scan and one follow-up scan 3 months later (96 +/- 10 days). For segmentation, 3D Slicer 2.5 software was used. Two segmentations were performed by two readers independently who were blinded to the scan dates. Tibial and femoral cartilage volume and surface were determined. Longitudinal and cross-sectional precision errors were calculated using the standard deviation (SD) and coefficient of variation (CV%=100x[SD/mean]) from the repeated measurements in each patient. The in vivo reproducibility was then calculated as the root mean square of these individual reproducibility errors. RESULTS: The cross-sectional root mean squared coefficient of variation (RMSE-CV) was 1.2, 2.2 and 2.4% for surface area measurements (femur, medial and lateral tibia respectively) and 1.4, 1.8 and 1.3% for the corresponding cartilage volumes. Longitudinal RMSE-CV was 3.3, 3.1 and 3.7% for the surface area measurements (femur, medial and lateral tibia respectively) and 2.3, 3.3 and 2.4% for femur, medial and lateral tibia cartilage volumes. CONCLUSION: The longitudinal in vivo reproducibility of cartilage surface and volume measurements in the knee using this segmentation method is excellent. To the best of our knowledge we measured, for the first time, the longitudinal reproducibility of cartilage volume and surface area in participants with mild to moderate OA.
参考中文摘要：
目的：本研究的目的是评估纵向重现软骨数量和面积测量中度骨关节炎（ OA ）的膝盖。材料与方法：我们分析了5磁共振成像（葛1.5T ，矢状位三维梯度回波同）数据集患者的骨关节炎（ OA ）膝关节（ Kellgren劳伦斯级第一和第二） 。扫描进行了两个：一个基线扫描和一个后续扫描3个月后（ 96 + / - 10天） 。分割，三维切片机2.5软件使用。两个分割是由两个独立的读者谁是失明的扫描日期。胫骨和股骨软骨体积和表面进行了测定。纵向和横截面精度误差计算的标准差（ SD ）和变异系数（简历％ = 100倍[自毁/平均] ）由反复测量每个病人。体内重现当时计算的均方根这些个人重现错误。结果：横断面根平均平方变异系数（ RMSE系数）为1.2 ， 2.2和2.4 ％的面积测量（股骨，胫骨内侧和外侧分别）和1.4 ， 1.8和1.3 ％的相应软骨卷。纵向RMSE系数为3.3 ， 3.1和3.7 ％的面积测量（股骨，胫骨内侧和外侧分别）和2.3 ， 3.3和2.4 ％ ，股骨，胫骨内侧和外侧软骨卷。结论：在体内纵向重复性软骨表面和体积测量膝关节使用此分割方法非常出色。以我们所知，我们测量，首次纵向重现软骨数量和面积在参加轻中度骨关节炎。
文献作者：
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作者单位：
Musculoskeletal Division, Department of Radiology, ASB-1, L-1, Room 003E, Harvard Medical School, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
文献来源：
Skeletal Radiology. 36(4):315-20, 2007 Apr.
NLM刊名：
Skeletal radiology 浏览此刊所有文献
出版国家：
Germany
所用语言：
English
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国内馆藏：
（需要消耗1医币）
国际馆藏：
PMID及链接：
17219231 http://www.syyxw.com/Archive/Detail/17219231
 
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