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1
参考中文标题：
关系Modic 1型变化与椎间盘退变：未来的MRI研究。
PMID及链接：
19096840 http://www.syyxw.com/Archive/Detail/19096840
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摘 要：
OBJECTIVE: The objective was to study the natural course of Modic type 1 change (M1) in relation to lumbar disc degeneration. MATERIALS AND METHODS: Twenty-four chronic low back pain (LBP) patients with M1 on lumbar spine were selected from 1,015 patients with magnetic resonance imaging from a follow-up study lasting for 18-74 months. Exclusion criteria were any other specific back disorder, age >/=60 years, or a recent spine operation. The association between the development of M1 and degenerative disc changes was studied using multivariate modeling (complex samples logistic regression). RESULTS: At baseline, 20 of 28 (71%) disc spaces with M1 had a decreased disc height (DH) and 16 of 28 (57%) a dark nucleus pulposus, but ten of 28 (36%) a very dark annulus fibrosus and a paradoxically bright nucleus pulposus albeit decreased DH. During follow-up, DH decreased in 13 of 28 (46%) and signal intensity of nucleus pulposus (DSI) in eight of 28 (29%) disc spaces with M1, but it increased in four (14%) discs. In those without M1, only few changes occurred. The larger the M1, the more likely was the DH low or decreased further. Both the presence and changes in M1 were associated with a decrease in DH and changes in DSI and bulges. CONCLUSION: The degenerative process in discs with adjacent M1 seems to be accelerated and leads to advanced and deforming changes with special morphologic features. M1 may be a sign of a pathologic degenerative process in the discovertebral unit.
参考中文摘要：
目标：目标是研究自然变化Modic 1型（ M1 ）余额与腰椎间盘退变。材料与方法： 24名慢性腰痛（枸杞多糖）对货币供应量M1患者腰椎选自1015例磁共振成像的后续研究持续18-74个月。排除标准，任何其他具体回到障碍，年龄“ / = 60年，或最近的脊椎手术。该协会的发展和M1腰椎间盘退变的变化进行了研究使用多变量模型（复杂样品logistic回归） 。结果：在基准， 20 28 （ 71 ％ ）光盘空间与M1减少了光盘高度（署）和16 28 （ 57 ％ ）的黑暗髓核，但10 28 （ 36 ％ ）一个非常黑暗的纤维环和自相矛盾的光明髓核虽然下降署。在后续行动中，卫生署在13个减少28个（ 46 ％ ）和信号强度髓核（ DSI公司）中有8个28 （ 29 ％ ）光盘空间与M1 ，但它增加了4个（ 14 ％ ）光盘。在那些没有货币供应量M1 ，只有少数发生变化。越大，货币供应量M1 ，就越有可能是低或卫生署进一步下降。双方的存在和变化，都与货币供应量M1减少署和变化DSI公司和凸起。结论：椎间盘退变过程中与相邻的货币供应量M1似乎是加速，并导致先进和变形的变化具有特殊形态。货币供应量M1可能是一个迹象，病理变性过程中discovertebral股。
出 处：
Skeletal radiology. 2009 Mar ,38 (3) :237-44
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2
参考中文标题：
骨折相关和特发性脊柱软骨病变：一个磁共振研究尸检标本病理相关。
PMID及链接：
19099302 http://www.syyxw.com/Archive/Detail/19099302
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摘 要：
OBJECTIVE: The aim of this study was to describe and compare the magnetic resonance (MR) and histological appearance of subchondral vertebral lesions that are idiopathic or that develop with vertebral fractures. MATERIALS AND METHODS: T1- and T2-weighted spin-echo images and radiographs were obtained in 81 cadaveric spine specimens. All subchondral vertebral lesions that were considered to be idiopathic or associated with vertebral end plate fractures were selected. Lesions due to growth disturbance were excluded. Radiographs and MR images were analyzed in consensus by two radiologists, and sampled specimens were analyzed by a pathologist. RESULTS: Eleven idiopathic and ten fracture-associated vertebral lesions were available. On T1-weighted images, all lesion signal intensity was low and homogeneous. On T2-weighted images, all idiopathic lesions showed a heterogeneous signal with a central low or intermediate signal component and a peripheral high or intermediate component. All but one fracture-related lesions showed a homogeneous intermediate to high signal intensity. Histological analysis of idiopathic lesions showed a central acellular fibrous connective tissue in all cases surrounded by loose connective tissue in nine cases. Herniated disk material and cartilage metaplasia were found in one lesion only. Fracture-associated lesions contained herniated disk material, necrotic tissue, and loose connective tissue with a peripheral component of loose fibrovascular connective tissue in four cases only. CONCLUSION: MR and histological appearance of idiopathic and fracture-associated subchondral vertebral lesions differ, suggesting that they might have a different origin.
参考中文摘要：
目的：本研究主要是描述和比较磁共振（先生）和软骨组织出现椎体病变的特发性或开发与脊椎骨折。材料与方法： T1的和T2加权自旋回波图像和X光片获得了在81个尸体脊柱标本。所有软骨椎体病变被认为特发性或与椎体终板骨折被选定。病变由于增长干扰被排除。 X光片和磁共振成像分析了共识两个放射，并采样标本进行了分析病理学家。结果： 11和10特发性骨折椎体病变的相关资料。在T1加权像，所有病灶信号强度低和均匀。在T2加权像，所有的特发性病变显示异构信号与中央低水平或中等信号部分和周围高中间部分。只有一个骨折有关的病灶均匀中间高信号强度。组织学分析显示，特发性病变的中央细胞纤维结缔组织在所有情况下，所包围疏松结缔组织中的9个案件。椎间盘突出材料和软骨化生中发现只有一个病变。骨折相关病变载椎间盘突出材料，坏死组织，并疏松结缔组织的外围组件松散纤维结缔组织只有4例。结论： MR和病理出现特发性和骨折椎体病变相关软骨不同，这表明它们可能有不同的原产地。
出 处：
Skeletal radiology. 2009 Mar ,38 (3) :245-53
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3
参考中文标题：
（ 18 ）的F - FDG PET显像分析的神经鞘瘤：增加SUVmax在延迟扫描与血管内皮生长因子升高/妇女议会论坛表达的肿瘤。
PMID及链接：
19089420 http://www.syyxw.com/Archive/Detail/19089420
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摘 要：
OBJECTIVE: In order to clarify the increased 2-deoxy-2-fluoro-(18)F-D: -glucopyranose ((18)F-FDG) accumulation in schwannoma by positron emission tomography (PET) analysis, immunohistochemical analysis for the factors involved in glucose transportation and vascular formation was performed. MATERIALS AND METHODS: Twenty-six patients with schwannoma (13 men and 13 women) with ages ranging from 27 to 75 years, who received whole body (18)F-FDG PET scan, were enrolled for the present study. The retention index (RI) was calculated by dividing the increase in the standardized uptake value (SUVmax) at the delayed scan by the SUVmax in the early scan. SUVmax and RI were compared with the histologic variables, including the expression of glucose transporters 1 and 3, hexokinase II, vascular endothelial growth factor/vascular permeability factor (VEGF/VPF), and microvascular density shown by CD31 immunohistochemistry. RESULTS: Mean SUVmax values in the early and delayed scans were 2.64 +/- 1.47 and 2.71 +/- 1.57 (mean +/- SD), respectively. RI was -2.5 +/- 21 (percentage). SUVmax showed a positive correlation with the tumor size (tumor size <5 cm, 2.06 +/- 0.72; >5 cm, 3.95 +/- 1.89; p < 0.05) and the microvascular density (negative density, 2.16 +/- 1.12; positive density, 3.56 +/- 1.67; p < 0.05). RI correlated with VEGF/VPF expression in the tumors (negative expression, -11 +/- 6.1; positive expression, 13 +/- 8.1; p < 0.05). Other factors showed no correlation with SUVmax or RI. CONCLUSIONS: Microvascular density and vascular permeability of the tumor are suggested to affect the enhanced (18)F-FDG accumulation in schwannoma.
参考中文摘要：
目的：为了澄清增加2 -脱氧- 2 -氟（ 18 ）消化不良： -葡萄糖（ （ 18 ） F -脱氧葡萄糖）积累的神经鞘瘤的正电子发射断层扫描技术（ PET ）分析，免疫组织化学分析涉及的因素葡萄糖运输和血管形成术。材料与方法： 26例神经鞘瘤（ 13男13女） ，年龄范围从27到75岁，谁收到全身（ 18 ）的F - FDG PET显像扫描，参加了本研究。保留指数（ RI ） ，计算除以增加的标准摄取值（ SUVmax ）在延迟扫描的SUVmax早期扫描。 SUVmax和RI进行了比较与病理变数，包括表达葡萄糖转运体1和第3 ，己糖激酶二，血管内皮生长因子/血管通透性因子（ VEGF /妇女议会论坛） ，与微血管密度表明CD31免疫组化。结果： SUVmax价值的早期和延迟扫描2.64 + / - 1.47和2.71 + / - 1.57 （平均+ / -的SD ）分别。扶轮社是-2.5 + / - 21 （百分比） 。 SUVmax呈正相关与肿瘤大小（肿瘤大小“ 5厘米， 2.06 + / - 0.72 ; ” 5厘米， 3.95 + / - 1.89 ; p “ 0.05 ）和微血管密度（负密度， 2.16 + / - 12月1日;积极密度， 3.56 + / - 1.67 ; p “ 0.05 ） 。扶轮社与血管内皮生长因子/妇女议会论坛表达的肿瘤（阴性表达， -11 + / - 6.1 ;阳性表达， 13 + / - 8.1 ; p “ 0.05 ） 。其他因素，表明无相关SUVmax或里。结论：微血管密度和血管通透性的肿瘤建议影响增强（ 18 ） F -脱氧葡萄糖积累的神经鞘瘤。
出 处：
Skeletal radiology. 2009 Mar ,38 (3) :261-6
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4
参考中文标题：
浏览器的说明。
PMID及链接：
19169725 http://www.syyxw.com/Archive/Detail/19169725
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出 处：
Skeletal radiology. 2009 Mar ,38 (3) :301-2
相关链接：
PubMed Google学术搜索
中文提供：
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