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1
参考中文标题：
对肌肉的放射（ESSR）欧洲学会2009年会亮点。
作者单位：
Musculoskeletal Centre, Chapeltown Road, Leeds, LS7 4SA, UK. andrew.grainger@leedsth.nhs.uk
PMID及链接：
19915834 http://www.syyxw.com/Archive/Detail/19915834
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出 处：
Skeletal radiology. 2010 Jan ,39 (1) :101-3
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中文提供：
2
参考中文标题：
循证放射学（第2部分）：是否有足够的研究，以支持到周边关节注射治疗呢？
作者单位：
Radiology, Orthopaedic University Hospital of Balgrist, Forchstrasse 340, 8008, Zürich, Switzerland. cynthia.peterson@balgrist.ch
PMID及链接：
19727709 http://www.syyxw.com/Archive/Detail/19727709
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摘 要：
INTRODUCTION: This review article addresses the best evidence currently available for the effectiveness of injection therapy for musculoskeletal conditions involving the peripheral joints. The research is presented by anatomical region and areas of controversy and the need for additional research are identified. DISCUSSION: Randomized controlled trials, meta-analyses and systematic reviews are lacking that address the effectiveness of therapeutic injections to the sternoclavicular, acromioclavicular, ankle and foot joints. No research studies of any kind have been reported for therapeutic injections of the sternoclavicular joint. With the exception of the knee, possibly the hip and patients with inflammatory arthropathies, research does not unequivocally support the use of therapeutic joint injections for most of the peripheral joints, including the shoulder. Additionally, controversy exists in some areas as to whether or not corticosteroids provide better outcomes compared to local anesthetic injections alone. CONCLUSION: When viscosupplementation injections are compared to corticosteroids in patients with osteoarthritis of the knee, the evidence supports the use of viscosupplementation for more prolonged improvement in outcomes, with corticosteroids being good for short-term relief.
参考中文摘要：
简介：本评论文章讨论了目前最好的证据的注射疗法对涉及周围关节肌肉骨骼的有效性提供条件。这项研究提出的部位和争议地区和需要进一步研究确定。讨论：随机对照试验，荟萃分析和缺乏系统的评语是针对注射的治疗效果的胸锁，肩，踝关节和脚。没有任何形式的研究，已为治疗胸锁关节注射。随着膝关节异常，可能与髋关节发炎arthropathies患者，研究并没有明确支持对周边缝最注射治疗联合使用，包括肩膀。此外，存在争论是否不皮质类固醇提供更好的结果相比，注射局部麻醉独自在有些领域。结论：当黏注射相比，与膝关节骨性关节炎患者皮质类固醇，有证据支持黏的成果进行更长时间的改善使用，皮质类固醇被短期的救济良好。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :11-8
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3
参考中文标题：
转化的证据知识：在医疗界忽视的任务。
作者单位：
Horten Centre for Patient Oriented Research and Knowledge Transfer, Raemistrasse 100, 8091, Zürich, Switzerland. johann.steurer@usz.ch
PMID及链接：
19821116 http://www.syyxw.com/Archive/Detail/19821116
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出 处：
Skeletal radiology. 2010 Jan ,39 (1) :1-3
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4
参考中文标题：
磁共振外观后上方labral剥离回绑架和在肱骨外旋。
作者单位：
Department of Radiology, 200 Lothrop St, Pittsburgh, PA 15213, USA. borrerocg@upmc.edu
PMID及链接：
19557410 http://www.syyxw.com/Archive/Detail/19557410
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摘 要：
OBJECTIVE: To describe the magnetic resonance appearance of posterosuperior labral peel back and determine the reliability of MR in the abducted and externally rotated (ABER) position for the prospective diagnosis of arthroscopically proven cases of posterosuperior labral peel back. METHODS: After approval by the institutional review board (IRB) of the University of Pittsburgh Medical Center, USA, databases of patients who underwent arthroscopy over a 2-year period for one of three clinical diagnoses [suspected type 2 superior labrum anterior to posterior (SLAP) tears, posterior instability, or multidirectional instability] were reviewed after anonymization by an honest broker. Sixty-three cases were selected by the following inclusion criteria: operative report documenting labral peel back in the ABER position, age <40 years, and preceding MR arthrogram evaluations with images in the ABER position (n=34). Inclusion criteria for the control group differed from those for the case group insofar as the operative note documented the absence of posterosuperior labral peel back (n=29). Cases and controls were randomized in one list and evaluated independently by two fellowship-trained musculoskeletal radiologists unaware of the surgical results and using a three-point grading system (0 = posterosuperior labrum normally positioned lateral/craniad to glenoid articular plane in ABER; 1 = posterosuperior labral tissue flush with the glenoid articular plane in ABER; 2 = posterosuperior labral tissue identified medial/caudal to glenoid articular plane in ABER). Only one image in ABER showing abnormal posterosuperior labral position was required for a grade of 1 or 2 to be assigned. Sensitivity, specificity, and positive and negative predictive value were calculated as well as the level of agreement between readers (kappa). RESULTS: Both readers assigned a grade of 2 to 25 of 34 patients with surgically proven labral peel back. Of the patients with surgically proven SLAP tears with peel back in ABER, reader A assigned a grade of 1 to seven patients and a grade of 0 to two patients, while reader B assigned a grade of 1 to eight patients and a grade of 0 to one patient. In the control group of 29 patients, reader A assigned 28 patients a grade of 0, one patient a grade 1, and no patients a grade 2. Reader B assigned 27 patients a grade of 0, two a grade 1, and no patients a grade 2. After the data had been dichotomized, with grade 1 and 0 cases both being regarded as negative, the MR criteria showed a sensitivity of 73%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 78%. The kappa coefficient of inter-rater agreement was excellent at 0.9, with disagreement in only four of 63 cases. In five of the 34 cases with peel back, a labral tear, defined by imbibition of contrast agent within a gap between labrum and underlying glenoid bone, could not be identified in standard planes in the neutral position. CONCLUSIONS: The use of the glenoid articular plane as a reference line to evaluate labral peel back in the abducted and externally rotated position is a fairly accurate and highly precise method for detection of posterosuperior labral peel back. Raising the possibility of labral peel back may help alert the arthroscopist to the presence of superior labral instability while the arm is abducted and externally rotated.
参考中文摘要：
目的：磁共振外观后上方labral剥离后确定的可靠性，在被绑架的议员和外部旋转（埃伯）的位置为未来的诊断证明案件关节后上方labral剥回。方法：核准后的机构审查委员会（ IRB ）的美国匹兹堡大学医学中心，美国，数据库的病人进行了关节镜谁超过了2年期三种临床诊断[怀疑2型上盂唇前到后（巴掌）眼泪，后不稳定，或多方位不稳定]进行了审查后，匿名的一个诚实的中间人。 63例被选定下列纳入标准：执行报告，记录labral皮回到埃伯立场，年龄“ 40年来，和前面的MR关节造影评价与图像埃伯立场（ 34例） 。纳入标准的对照组不同于组的情况下，只要执行注意到没有记载后上方labral皮尔回（ 29例） 。病例组和对照，随机在一个清单和评估的两个独立研究训练肌肉骨骼放射知道手术结果和使用三点分级系统（ 0 =后上方唇侧通常定位/ craniad以盂关节面埃伯; 1 =冲洗后上方labral组织的盂关节面埃伯; 2 =后上方labral组织确定内侧/尾，以盂关节面埃伯） 。只有一个形象埃伯显示异常后上方labral立场是所需要的等级的1或2要指派。敏感性，特异性，阳性和阴性预测值分别计算，以及一级读者之间的协议（ Kappa值） 。结果：读者指派一个年级的2至25日的34例手术证实labral剥离回来。患者的手术证明巴掌眼泪与皮尔在埃伯，读者指派一个年级的1名病人和等级0到2例，而读者乙指派一个年级的1至8名病人和等级0 1例。对照组29例，读者指定的28例的0级， 1级1例，无患者二级。读者乙指派27例级为0 ，两个1级，也没有病人二级。数据公布后，已再二，与1级和零案件都被视为消极的，标准的磁共振表现出的敏感性为73 ％ ，特异性为100 ％ ，阳性预测值为100 ％ ，阴性预测值的78 ％ 。系数的转录间协议是出色的评分是0.9 ，与分歧中，只有4个63例。在五年的34例剥离回，一个labral撕裂，界定吸内的造影剂之间存在着差距和潜在的关节唇骨，无法确定标准的飞机在中立的立场。结论：使用盂关节面作为参考线，以评估labral皮早在被绑架和外部旋转的立场是相当准确和高度精确的检测方法的后上方labral皮回来。提高的可能性labral皮回可帮助提醒arthroscopist的存在上级labral不稳定而ARM是绑架和外部旋转。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :19-26
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5
参考中文标题：
与luxatio万寿菊肱骨MRI表现。
作者单位：
Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA.
PMID及链接：
19730855 http://www.syyxw.com/Archive/Detail/19730855
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摘 要：
OBJECTIVE: Luxatio erecta humeri is a rare type of inferior glenohumeral dislocation with a unique radiographic appearance; however, the magnetic resonance imaging findings associated with this dislocation have not been described in the radiology literature. The purpose of this study is to identify magnetic resonance imaging findings associated with this uncommon type of glenohumeral dislocation. MATERIALS AND METHODS: The magnetic resonance imaging features of four patients with clinical and radiographic evidence of luxatio erecta humeri were reviewed retrospectively by two musculoskeletal-trained radiologists. The reported mechanism of injury in all four patients was falling. The MR imaging examinations were evaluated for the presence of rotator cuff and biceps tendon pathology, glenoid labrum pathology, joint capsule and glenohumeral ligament injury, fractures and bone marrow contusions, articular cartilage injury, and joint effusions. RESULTS: All four patients demonstrated pathology of the glenohumeral joint. Three of the four patients demonstrated rotator cuff tears, including large full thickness tears of the supraspinatus and infraspinatus tendons in two patients, and small full thickness tear of the supraspinatus tendon with partial thickness tear of the infraspinatus tendon in the third patient. In the two patients with large full thickness tears of the supraspinatus and infraspinatus tendons, one patient demonstrated tearing of the subscapularis tendon with dislocation of a partially torn long head of the biceps tendon, and the second patient demonstrated full thickness tearing of the intra-articular biceps tendon. All four patients demonstrated injuries to the glenoid labrum and both anterior and posterior bands of the inferior glenohumeral ligament. Contusions or fractures of the humeral head were seen in two of the patients. Three of the four patients demonstrated cartilage abnormalities including a focal cartilage defect in the anterior inferior glenoid in one patient, and cartilage surface irregularity of the glenoid in the other two patients. CONCLUSION: Common magnetic resonance imaging findings in patients with a prior luxatio erecta humeri dislocation include rotator cuff tears, injury to the glenoid labrum, and injury to both the anterior and posterior bands of the inferior glenohumeral ligament. These findings are compatible with the mechanism of dislocation in luxatio erecta, and noting these findings on magnetic resonance imaging may suggest that the patient has sustained a prior inferiorly directed glenohumeral dislocation such as luxatio erecta.
参考中文摘要：
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :27-33
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6
参考中文标题：
内部和跨审查员的肩峰下撞击指数的可靠性。
作者单位：
Ribeir?o Preto School of Medicine, University of S?o Paulo, Paineiras St, Monte Alegre, 14049-900, Ribeir?o Preto, SP, Brazil.
PMID及链接：
19756589 http://www.syyxw.com/Archive/Detail/19756589
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摘 要：
OBJECTIVE: The present study aimed to assess the reliability of intra and inter-examiner subacromial impingement index (SII) measures obtained from radiographs. MATERIALS AND METHODS: Thirty-six individuals were enrolled and divided into two groups: control group, composed of 18 volunteers in good general health without shoulder problems, and a group of 18 patients with subacromial impingement syndrome (SIS). Radiographic images were taken with the dominant upper limb in neutral rotation, while the volunteers held their arm at 90 degrees of abduction in the frontal plane. The beam of radiation at 30 degrees craniocaudal inclination was used to provide an antero-posterior image view. Three blinded examiners each performed three measurements from the subacromial space (SS) and the anatomical neck of the humerus (NH). The SII was calculated as the ratio of the SS and the NH measures. The mean values of SII were compared using t-tests. The intra-class correlation coefficient (ICC) was used to assess intra- and inter-examiner reliability of the measures. RESULTS: The mean values of SII were greater for the control group (0.12) than for the SIS group (0.08; p = 0.0071). SII measurements showed excellent intra (0.96-0.99) and inter-examiner reliability (0.94) for both the control and SIS group. CONCLUSION: The results of this study show the potential use of the SII; a greater mean value for the control group compared to the SIS group and excellent reliability for intra- and inter-examiner measurement. Validation studies of the index should be conducted to correlate the index with clinical findings from subacromial impingement syndrome.
参考中文摘要：
目的：本研究旨在评估内部和区域之间的可靠性检验肩峰下撞击指数（SII）时获得的X光片的措施。材料与方法：36人报读，并分成两组：无肩伤困扰对照组，18健康情况大致良好志愿者组成划分，以及18肩峰下撞击综合征（SIS）的病人。 X光图像采取中立的主流旋转上肢，而志愿者举行了90度的绑架在额面的手臂。在辐射的头尾倾角30度的光束被用于提供安特罗，后形象。每个演出三从肩峰下空间（SS）的3个测量和肱骨（信息NH）解剖颈蒙蔽考官。此外，SiI计算作为SS和比例的NH措施。对精工的平均值进行了比较采用t检验。该组内相关系数（ICC）是用于评估内部和跨审查员措施的可靠性。结果：SII的平均值分别是更大的对照组（0.12比申根信息系统组）（0.08，p = 0.0071）。精工仪器测量显示，在控制和SIS的优秀内部（0.96-0.99）和机构检验的可靠性（0.94）。结论：本研究结果表明了该精工仪器公司的潜在用途;为对照组更大的平均值相比，SIS的组和内部良好的可靠性和机构检验测量。该指数的验证研究应当进行关联与肩峰下撞击综合征临床表现指数。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :35-9
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7
参考中文标题：
评价前压力造影，超声及磁共振成像距腓韧带损伤。
作者单位：
Department of Orthopaedics, Shimane University School of Medicine, 89-1, Enya-cho, Shimane Izumo, 693-8501, Japan. kazuoa@med.shimane-u.ac.jp
PMID及链接：
19685050 http://www.syyxw.com/Archive/Detail/19685050
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摘 要：
OBJECTIVE: The purpose of this study was to clarify the efficacy of stress radiography (stress X-P), ultrasonography (US), and magnetic resonance (MR) imaging in the detection of the anterior talofibular ligament (ATFL) injury. METHODS: Thirty-four patients with ankle sprain were involved. In all patients, Stress X-P, US, MR imaging, and arthroscopy were performed. The arthroscopic results were considered to be the gold standard. The imaging results were compared with the arthroscopic results, and the accuracy calculated. RESULTS: Arthroscopic findings showed ATFL injury in 30 out of 34 cases. The diagnosis of ATFL injury with stress X-P, US, MR imaging were made with an accuracy of 67, 91 and 97%. US and MR imaging demonstrated the same location of the injury as arthroscopy in 63 and 93%. CONCLUSION: We have clarified the diagnostic value of stress X-P, US, and MR imaging in diagnosis of ATFL injury. We obtained satisfactory results with US and MR imaging.
参考中文摘要：
目的：本研究的目的是要澄清的前距腓韧带的应力检测放射成像（应力XP中），超声（美国）和磁共振（MR）成像效果（ATFL）损伤。方法：34例踝关节扭伤的患者参与。在所有患者中，应力XP中，美国，磁共振成像和关节镜的演出。在关节镜结果被认为是黄金标准。该成像结果进行了比较与关节镜结果，计算的准确性。结果：关节镜结果显示出34宗，30 ATFL受伤。在ATFL压力XP中，美国损伤的诊断，磁共振成像会上提出了67个，91和97％的准确性。美国和磁共振成像显示了在63和93％，关节损伤的同一位置。结论：我们已经澄清了应力的诊断价值XP中，美国，和MR的ATFL损伤诊断成像。我们获得了与美国和磁共振成像令人满意的结果。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :41-7
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8
参考中文标题：
近端的尺谱synostosis发展。
作者单位：
Winnipeg Regional Health Association Program of Genetics and Metabolism, University of Manitoba, Winnipeg, MB, Canada. aelliott@hsc.mb.ca
PMID及链接：
19669136 http://www.syyxw.com/Archive/Detail/19669136
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摘 要：
OBJECTIVE: Proximal radioulnar synostosis is a rare upper limb malformation. The elbow is first identifiable at 35 days (after conception), at which stage the cartilaginous anlagen of the humerus, radius and ulna are continuous. Subsequently, longitudinal segmentation produces separation of the distal radius and ulna. However, temporarily, the proximal ends are united and continue to share a common perichondrium. We investigated the hypothesis that posterior congenital dislocation of the radial head and proximal radioulnar fusion are different clinical manifestations of the same primary developmental abnormality. MATERIALS AND METHODS: Records were searched for "proximal radioulnar fusion/posterior radial head dislocation" in patients followed at the local Children's Hospital and Rehabilitation Centre for Children. Relevant radiographic, demographic and clinical data were recorded. Ethics approval was obtained through the University Research Ethics Board. RESULTS: In total, 28 patients met the inclusion criteria. The majority of patients (16) had bilateral involvement; eight with posterior dislocation of the radial head only; five had posterior radial head dislocation with radioulnar fusion and two had radioulnar fusion without dislocation. One patient had bilateral proximal radioulnar fusion and posterior dislocation of the left radial head. Nine patients had only left-sided involvement, and three had only right-sided involvement.The degree of proximal fusion varied, with some patients showing 'complete' proximal fusion and others showing fusion that occurred slightly distal to the radial head: 'partially separated.' Associated disorders in our cohort included Poland syndrome (two patients), Cornelia de Lange syndrome, chromosome anomalies (including tetrasomy X) and Cenani Lenz syndactyly. CONCLUSION: The suggestion of a developmental relationship between posterior dislocation of the radial head and proximal radioulnar fusion is supported by the fact that both anomalies can occur in the same patient. Furthermore, both anomalies can be seen in different patients with the same genetic diagnosis, further supporting the notion that these defects are developmentally related. Posterior dislocation of the radial head and radioulnar fusion are considered to be related primary developmental anomalies of radioulnar differentiation/segmentation. We speculate that the eventual specific defect of this spectrum is influenced by very subtle differences in developmental timing. This is in contrast to patients with transverse forearm defects who can also display radial head dislocation but in an anterior or lateral direction. This direction of dislocation is seen when an abnormal force is exerted on a normally formed radial head later in development or postnatally in disorders such as multiple osteochondromatosis and various mesomelic dysplasias, or as a result of trauma.
参考中文摘要：
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :49-54
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9
参考中文标题：
早期发现的类风湿和糜烂性与高分辨率单光子发射计算机断层扫描手指关节骨关节炎改变，以及它们之间的差异。
作者单位：
Rheumatology, Department of Endocrinology, Diabetology and Rheumatology, Heinrich-Heine University, Düsseldorf, Germany.
PMID及链接：
19669137 http://www.syyxw.com/Archive/Detail/19669137
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摘 要：
OBJECTIVE: To evaluate high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) for the detection of bony alterations in early rheumatoid arthritis (ERA), early osteoarthritis (EOA) of the fingers and healthy controls. METHODS: The clinically dominant hands of 27 patients (13 ERA, nine EOA, five healthy controls) were examined by MPH-SPECT and bone scintigraphy. Additionally, magnetic resonance imaging (MRI) was performed in the ERA patients. Number of affected joints, localisation, pattern of tracer distribution and joint involvement were scored. Quantitative analysis was achieved by measurement of the region of interest (ROI) in all patients. The MPH-SPECT and MR images were fused in the ERA group. RESULTS: Bone scintigraphy detected fewer joints (26 joints,13/22 patients) with increased tracer uptake than did MPH-SPECT (80 joints, 21/22 patients). Bone scintigraphy did not show recognisable uptake patterns in any group of patients. With MPH-SPECT central tracer distribution was typical in ERA (10/13 patients, EOA 2/9). In contrast, an eccentric pattern was found predominantly in EOA (7/9, ERA 2/13). Normalised counts were 4.5 in unaffected joints and up to 222.7 in affected joints. The mean uptake values in affected joints were moderately higher in the EOA patients (78.75, and 62.16 in ERA). The mean tracer uptake in affected joints was approximately three-times higher than in unaffected joints in both groups (ERA 3.64-times higher, EOA 3.58). Correlation with MR images revealed that bone marrow oedema and erosions matched pathological tracer accumulation of MPH-SPECT in 11/13. MPH-SPECT demonstrated increased activity in 2/13 patients with normal bone marrow signal intensity and synovitis seen on MR images. CONCLUSION: MPH-SPECT is sensitive to early changes in ERA and EOA and permits them to be distinguished by their patterns of uptake.
参考中文摘要：
目的：探讨高分辨率多针孔单光子发射型计算机断层（英里断层显像）的骨改建检测早期类风湿关节炎（失），早期骨关节炎（有效瓣）的手指和健康对照组。方法：27例患者的临床主要手（13年代，9有效瓣，5名健康对照）的检查，公共卫生硕士，显像和骨显像。此外，磁共振成像（MRI）是进行电子逆向拍卖的病人。受影响的关节，本地化，示踪剂分布格局和共同参与了一些成绩。定量分析是实现由感兴趣区域（ROI）的测量所有患者。在公共卫生硕士，SPECT和MR图像融合在时代集团。结果：骨显像发现少关节（26接头，13/22患者增加示踪剂摄取比没有公共卫生硕士，显像（80个关节，21/22例））。骨显像没有显示任何组患者识别的吸收模式。随着公共卫生硕士，中央显像示踪剂分布典型自责（10/13例，有效瓣2 / 9）。相反，一个古怪的格局被发现主要是在有效瓣（7 / 9，自责2 / 13）。正常化计数影响关节在4.5至222.7，并在受影响的关节。在受影响的关节平均摄取值温和上涨的有效瓣病人（78.75，并在失分62.16）。在受影响的关节示踪平均摄取约3倍以上，在两组影响关节（3.64自责，倍高，有效瓣3.58）。与磁共振成像对比表明，骨髓水肿和糜烂匹配的公共卫生硕士病理示踪剂的积累，在11月13日显像。公共卫生硕士断层显像显示的活动增加2 / 13例正常骨髓信号强度和磁共振成像看到滑膜炎患者。结论：公共卫生硕士断层显像，是敏感的年代和有效瓣早期变化，并允许他们是通过吸收杰出的模式。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :55-61
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参考中文标题：
作者单位：
Radiology, Orthopaedic University Hospital of Balgrist, Forchstrasse 340, 8008 Zürich, Switzerland. cynthia.peterson@balgrist.ch
PMID及链接：
19730856 http://www.syyxw.com/Archive/Detail/19730856
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摘 要：
INTRODUCTION: This review article addresses the best evidence currently available for therapeutic injection therapy for conditions targeting the spine and sacroiliac joints. The article is presented by spinal region. Controversies and areas of interest for further studies are identified. DISCUSSION: There is conclusive evidence supporting the effectiveness of the caudal approach for the administration of epidural steroid injections for patients with low back pain from a variety of causes. In general, there is moderate-to-strong evidence supporting the use of transforaminal therapeutic epidural injections for lumbar nerve-root compression and facet injections for joint pain arising from these joints in the cervical, thoracic and lumbar spine, but further subgroup analysis is needed to help predict which specific patients may receive the most benefit from these procedures. CONCLUSION: No randomized controlled trials, meta-analyses or systematic reviews addressing the effectiveness of therapeutic sacroiliac joint injections have been found. For some injections, corticosteroids may not provide better outcomes compared to local anesthetic injections alone.
参考中文摘要：
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :5-9
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家族肿瘤钙化和骨化，高磷血症综合征是不同的同一种病的表现：在GALNT3新型错义突变。
作者单位：
Department of Orthopaedic Surgery, Vinodhagan Memorial Hospital and Dr. Joseph's Ortho Clinic, Thanjavur, India.
PMID及链接：
19830424 http://www.syyxw.com/Archive/Detail/19830424
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OBJECTIVE: To report on the biochemistry and clinical and genetic findings of two siblings, the younger sister presenting with recurrent bone pain of the radius and ulna, and medullary sclerosis, and the older brother with soft tissue calcific deposits (tumoral calcinosis) but who later developed bone pain. Both were found to be hyperphosphaturic. MATERIALS AND METHODS: The index family comprised four individuals (father, mother, brother, sister). The affected siblings were the offspring of a non-consanguineous Indian family of Tamil origin. Bidirectional sequencing was performed on the DNA from the index family and on 160 alleles from a population of 80 unrelated unaffected control individuals of Tamil extraction and 72 alleles from individuals of non-Tamil origin. RESULTS: Two symptomatic siblings were found to harbour previously unreported compound heterozygous missense UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-transferase; GALNT3) mutations in exon 4 c.842A>G and exon 5 c.1097T>G. This sequence variation was not detected in the control DNA. This is the first report of siblings exhibiting stigmata of familial tumoral calcinosis and hyperostosis-hyperphosphataemia syndrome with documented evidence of autosomal recessive missense GALNT3 mutations. CONCLUSION: The findings from this family add further evidence to the literature that familial tumoral calcinosis and hyperostosis-hyperphosphataemia syndrome are manifestations of the same disease and highlight the importance of appropriate metabolic and genetic investigations.
参考中文摘要：
目的：报告和临床生化和两个兄弟，妹妹同尺桡骨性疼痛演示和骨髓硬化的基因发现，和哥哥与软组织（肿瘤沉着症），但后来谁钙化存款开发骨痛。两人都发现hyperphosphaturic。材料与方法：该指数系列包括四个人（父亲，母亲，兄弟，姐妹）。受影响的兄弟姐妹是一个非后代，近亲印度的泰米尔族家庭。双向测序的对象是从索引家庭的DNA和160等位基因从80无关的泰米尔提取和72等位基因未受控制的非个人，泰米尔族个人的人口。结果：两个症状的兄弟姐妹港发现以前未复合杂义的UDP - N -乙酰- D -氨基半：多肽N - acetylgalactosaminyltransferase 3（半乳糖转移酶; GALNT3）外显子4 c.842A“G和5角外显子突变1097T“湾这个序列变异，没有检出控制的DNA。这是展示痕家族肿瘤钙化和骨化，高磷血症与记载的常染色体隐性遗传错义突变的证据综合征GALNT3兄弟的第一次报告。结论：从这个家庭的调查结果进一步补充证据文学家族肿瘤钙化和骨化，高磷血症综合征是同一种疾病的表现，并强调适当的代谢和遗传调查的重要性。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :63-8
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骨旁骨肉瘤骨肉瘤dedifferentiating进入毛细血管扩张：对裂解变化和成像液体腔的重要性。
作者单位：
PMID及链接：
19826810 http://www.syyxw.com/Archive/Detail/19826810
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出 处：
Skeletal radiology. 2010 Jan ,39 (1) :69; author reply 71
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13
参考中文标题：
第一次报告了坚实的变异动脉瘤样骨囊肿的全部骶骨。
作者单位：
Department of Traumatology, Klinikum rechts der Isar, Technical University Munich, Ismaningerstrasse 22, 81675, Munich, Germany. vester@uchir.me.tum.de
PMID及链接：
19603163 http://www.syyxw.com/Archive/Detail/19603163
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摘 要：
We report on a 19-year-old woman with a rapidly growing, solid variant of aneurysmal bone cyst (solid ABC) in the right part of the lateral mass of the sacrum. On admission, the magnetic resonance imaging (MRI) scan disclosed an inhomogeneous low intensity mass right of the centre of the os sacrum with a diameter of 38 x 64 mm and a height of 56 mm on T1 and T2 weighted images. The mass showed homogenous high signal intensity on Gd-enhanced images. Computed tomography demonstrated an expansile osteolytic lesion and (99m)Tc-methylene diphosphonate bone scintigraphy revealed uniform accumulation in the lesion. The histological evaluation showed a proliferation of fibroblasts, histiocytes, chronic inflammatory cells and numerous multinucleated giant cells. Nevertheless, the cells were devoid of nuclear atypia. A cystic component was not observed. In spite of thorough curettage, the patient suffered from recurrence and severe neurological deficits. A review of the literature revealed no previous cases of solid ABC in the sacrum.
参考中文摘要：
我们报告一个19岁女子与快速发展，固体变动脉瘤样骨囊肿（固体ABC ）的正确的部分侧块骶骨。入院，磁共振成像（ MRI ）扫描发现一不均匀低强度大规模权利中心的全部骶骨直径为38 × 64毫米，而高度的五十六毫米的T1和T2加权像。大众表明均匀高信号钆增强图像。计算机断层扫描显示出一个膨胀溶骨性病变（九十九米）锝-甲基diphosphonate骨显像显示统一积累的病变。组织学评价表明，成纤维细胞增殖，组织球，慢性炎性细胞和许多多核巨细胞。然而，细胞缺乏核异型性。囊状部分不遵守。尽管彻底刮除，病人因复发和严重的神经功能缺损。文献复习没有发现以前的案件坚实的美国广播公司在骶骨。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :73-7
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参考中文标题：
非典型的迅速进展涉及在使用聚丙烯腈膜透析病人髋关节淀粉样变性。
作者单位：
Department of Radiology, University of Wisconsin Hospital and Clinics, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue CSC E3/311, Madison, WI 53792-3252, USA. klee2@uwhealth.org
PMID及链接：
19707759 http://www.syyxw.com/Archive/Detail/19707759
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摘 要：
Amyloidosis related to dialysis is a well-known complication affecting many organ systems, in particular the musculoskeletal system. In 1985 Shirahama et al. (Biochem Biophys Res Commun 53:705-709, 1985) identified beta-2 microglobulin (MG) as the offending constituent by using protein purification techniques. Amyloidosis has been increasing in prevalence because of longer life spans and increased chronic medical conditions such as end-stage renal disease. When dialysis-related amyloidosis involves the musculoskeletal system, it affects the shoulder girdle, the so called shoulder pad sign, the wrist, hip, knee, and spine (Resnick, Diagnosis of bone and joint disorders, 4th edn., pp. 2054-2058 and 2176-2183, 2002). Other osteoarticular manifestations of amyloidosis include osteoporosis, lytic lesions, and pathologic fractures. It has been well documented that the prevalence of amyloid is dependent on duration of dialysis-over 90% in patients on dialysis for over 7 years (Jadoul, Nephrol Dial Transplant 13:61-64, 1998). However, a recent changeover to high-flux membranes used in hemofiltration has been reported to delay its onset (Campistol et al., Contrib Nephrol 125:76-85, 1999). We report on the radiographic, nuclear medicine, and computed tomography (CT) findings of osteoarticular amyloidosis involving the hip, and sequence its atypical rapid onset. The imaging, histopathological findings, and differential diagnosis are discussed.
参考中文摘要：
透析相关的淀粉样变性是一个众所周知的并发症，影响到许多器官系统，尤其是肌肉骨骼系统。 1985年白滨等。 （生化Biophys杂志Commun 53:705-709，1985年）确定的β- 2微球蛋白组成的冒犯（MG）的使用蛋白质纯化技术。淀粉样变有所增加，由于更长的寿命普遍增加，如慢性疾病的最终阶段的肾脏疾病。当透析相关性淀粉样涉及肌肉骨骼系统，它影响到肩胛带，即所谓的垫肩的迹象，手腕，臀部，膝盖和脊椎（雷斯尼克，骨与关节疾病，第四edn诊断。，页。2054 - 2058和2176年至2183年，2002年）。淀粉样变性的其他表现包括关节骨质疏松，溶骨病变，病理性骨折。据记录表明，淀粉样患病率透析的时间依赖性超过90％的患者超过7年来透析（Jadoul，Nephrol拨号移植13:61-64，1998年）。不过，最近更换高通量血液滤过膜的使用已经报告推迟发病（Campistol等。，的contrib Nephrol 125:76-85，1999）。我们报告的影像学，核医学，计算机断层扫描（CT）的涉及髋关节淀粉样结果，以及快速序列及其非典型发病。的影像，病理结果，鉴别诊断进行了讨论。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :79-83
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15
参考中文标题：
半肢骨骺发育异常：X线及磁共振成像的特点和完整和不完全切除的临床结果。
作者单位：
The Musculoskeletal Oncology Group, The Catholic University of Korea, Uijungbu, Gyunggido, Korea. wjbahk@catholic.ac.kr
PMID及链接：
19813010 http://www.syyxw.com/Archive/Detail/19813010
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OBJECTIVES: The objectives of this communication were to discuss radiographic and magnetic resonance (MR) imaging manifestations and clinical outcome after complete and incomplete resection of the mass of dysplasia epiphysealis hemimelica (DEH). MATERIALS AND METHODS: Clinical records, radiographs, and MR images of eight patients with DEH were retrospectively examined. Six patients were treated by complete excision of the lesional mass, and two patients were treated by incomplete resection at our University Hospitals during the period from 1980 to 2006. RESULTS: We found that, unlike in osteochondroma, DEH was radiographically not clearly separable from the underlying or host bone with preserved cortical bone and marrow continuity. The finding in the talus distinguished DEH from (osteochondroma-like) parosteal osteosarcoma, in which a radiolucent demarcation line clearly separated the tumor from the host bone. The DEH mass had a well-defined low to intermediate signal intensity on T1-weighted images and an intermediate to high signal intensity on T2-weighted images, with irregularity of the articular surface. Simple excision was performed in all patients. The excision was complete in six patients and incomplete in two patients whose lesions was juxta-articular in the ankle and articular in the knee, respectively. The residual mass slowly absorbed and vanished, resulting in mild flaring of the affected portion of the epiphysis. No local recurrence or complication was seen in any of the eight patients. CONCLUSIONS: Although the radiographic signs of DEH are characteristic, (osteochondroma-like) parosteal osteosarcoma should be differentiated from DEH when there is a radiolucent separation line between the mass and host bone in the talus. Simple excision was effective in the management of DEH if the deformity was not complicated. Incompletely excised masses resolved and vanished with time.
参考中文摘要：
目标：本沟通的目的是讨论后，完全和不完全的大规模切除射线和磁共振（MR）影像学表现及临床结果半肢骨骺发育不良（DEH系统）。材料与方法：临床记录，X线，和电液控制系统的8个患者进行回顾性磁共振成像检查。 6例的治疗质量完全切除病灶，2例经我们的大学医院治疗不完全切除，在1980年至2006年。结果：我们发现，不同于软骨，X线片DEH系统是没有明确分离从底层或主机与保存皮质骨骨和骨髓的连续性。从（骨软骨瘤样）骨旁骨肉瘤，其中一射线分界线明显脱离宿主骨肿瘤中发现距骨杰出代。大规模的电液控制系统进行了明确界定在T1低信号强度中间加权图像和在T2中间一个高信号强度加权图像，与关节面不规则。简单切除，所有患者。完整的切除6例和2例，其病变是关节旁的踝关节和膝关节，分别不完整的。大量的剩余慢慢吸收和消失，造成轻度的骨骺受影响的部分燃烧。无局部复发或并发症看到8个病人是没有。结论：虽然DEH系统的影像学特征迹象，（骨软骨瘤样）骨旁骨肉瘤，应区别时，从DEH系统之间存在的质量和宿主骨放射线分离的距骨线。简单切除是有效的DEH系统的管理，如果畸形并不复杂。不完全切除群众解决，随着时间的推移消失。
出 处：
Skeletal radiology. 2010 Jan ,39 (1) :85-90
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16
参考中文标题：
一年的回顾：在肌肉骨骼放射学和生物学的最新进展。
作者单位：
Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA. rkamath@partners.org
PMID及链接：
19902209 http://www.syyxw.com/Archive/Detail/19902209
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出 处：
Skeletal radiology. 2010 Jan ,39 (1) :93-6
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