设为首页 | 收藏本站

提示：目前本站文摘的参考中文大部分是机器翻译结果，尚且存在不足之处。希望广大用户积极参与翻译修改。

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

Painful skeletal metastases are a common problem in cancer patients. Although external beam radiation therapy is the current standard of care for cancer patients who present with localized bone pain, 20-30% of patients treated with this modality do not experience pain relief, and few further options exist for these patients. For many patients with painful metastatic skeletal disease, analgesics remain the only alternative treatment option. Recently, image-guided percutaneous methods of tumor destruction have proven effective for treatment of this difficult problem. This review describes the application, limitations, and effectiveness of percutaneous ablative methods including ethanol, methyl methacrylate, laser-induced interstitial thermotherapy (LITT), cryoablation, and percutaneous radiofrequency ablation (RFA) for palliation of painful skeletal metastases. [References: 61]

参考中文摘要：

痛苦的骨转移是一个共同的问题在癌症患者。虽然体外放射治疗是目前标准的护理癌症患者谁与本地化本骨痛， 20-30 ％的患者这种方式不会遇到疼痛缓解，很少有其他选择存在这些病人。对于许多患者痛苦的转移性骨骼疾病，止痛仍然是唯一的选择治疗方法。最近，图像引导下经皮穿刺方法肿瘤破坏已证明有效的治疗这一难题。本文介绍的应用，限制和有效性的方法，包括经皮烧蚀乙醇，甲基丙烯酸甲酯，激光诱导间质热疗（利特），刀，经皮射频消融（ RFA ）为减轻痛苦的骨转移。 [参考文献： 61 ]

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

OBJECTIVE: To relate the magnetic resonance imaging (MRI) appearance of autologous chondrocyte implantation (ACI) in the knee in the 1st postoperative year with other knee features on MRI and with clinical outcome. DESIGN AND METHODS: Forty-nine examinations were performed in 49 patients at 1 year after ACI in the knee. Forty-one preoperative magnetic resonance (MR) examinations were also available. The grafts were assessed for smoothness, thickness in comparison with that of adjacent cartilage, signal intensity, integration to underlying bone and adjacent cartilage, and congruity of subchondral bone. Presence of overgrowth and bone marrow appearance beneath the graft were also assessed. Presence of osteophyte formation, further cartilage defects, appearance of the cruciate ligaments and the menisci were also recorded. An overall graft score was constructed, using the graft appearances. This was correlated with the knee features and the Lysholm score, a clinical self-assessment score. The data were analysed by a Kruskal-Wallis H test followed by a Mann-Whitney U test with Bonferroni correction as post-hoc test. RESULTS: Of 49 grafts, 32 (65%) demonstrated complete defect filling 1 year postoperatively. General overgrowth was seen in eight grafts (16%), and partial overgrowth in 13 grafts (26%). Bone marrow change underneath the graft was seen; oedema was seen in 23 grafts (47%), cysts in six grafts (12%) and sclerosis in two grafts (4%). Mean graft score was 8.7 (of maximal 12) (95% CI 8.0-9.5). Knees without osteophyte formation or additional other cartilage defects (other than the graft site) had a significantly higher graft score than knees with multiple osteophytes (P=0.0057) or multiple further cartilage defects (P=0.014). At 1 year follow-up improvement in the clinical scores was not significantly different for any subgroup. Knees with a graft score of 8 points or greater had a better improvement of the clinical score than those of 7 points or fewer. CONCLUSIONS: At 1 year follow-up after ACI, higher graft scores are associated with an overall better preserved knee joint. ACI improves the clinical outcome, but there is no statistically significant correlation of graft score and clinical outcome.

参考中文摘要：

目的：涉及的磁共振成像（ MRI ）出现自体软骨细胞移植（脑梗死）在膝部手术后的第1年与其他膝关节功能磁共振成像与临床结果。设计和方法： 49个考试进行了49例在1年后脑梗塞的膝盖。 41个术前磁共振（先生）考试也可以。移植被分摊的光滑，厚度相比，与邻近的软骨，信号强度，一体化的基本骨骼和邻近软骨和一致性的软骨。存在过度和骨髓移植的外观下面还评估。在场的骨赘形成，进一步软骨缺损，外观十字韧带和半月板亦录。整体移植评分建造，使用移植露面。这是与膝关节功能和Lysholm评分，临床自我评估评分。这些数据进行分析的非参数检验H测试之后，以Mann - Whitney U检验与Bonferroni校正后的临时检验。结果： 49例， 32 （ 65 ％）表现出完整的缺陷填补，术后1年。一般过度，看到在8移植（ 16 ％），并在13个部分过度移植（ 26 ％）。骨髓移植改变底下看到;水肿被认为在23移植（ 47 ％），囊肿6例（ 12 ％）和硬化两个移植（ 4 ％）。平均移植评分为8.7 （最大12 ）（ 95 ％ CI为8.0-9.5 ）。膝盖没有骨赘形成或增加其他软骨缺损（除移植网站）有一个显着高于移植评分超过膝盖与多个osteophytes （ P值0.0057 ）或多个进一步软骨缺损（ P值0.014 ）。在一年的后续改善临床分数无显着差异的任何分组。膝盖与移植评分为8分或更高了一个更好的改善临床评分比7分或更少。结论：在1年后的后续行动脑梗死，高移植分数都与整体更好的保存膝关节。脑梗死提高临床疗效，但没有统计学意义的相关性移植物抗评分和临床疗效。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

OBJECTIVE: To describe the MRI features of extraskeletal myxoid chondrosarcoma in comparison with clinicopathologic findings. DESIGN AND PATIENTS: The study comprised 12 male subjects and seven female subjects with a mean age of 53 years (range 16-76 years). MRI findings, evaluated by two radiologists with agreement by consensus, were compared for histopathologic features. RESULTS: The tumor size ranged from 2.0 cm to 20.0 cm (mean 8.9 cm). Fusion gene transcripts could be detected in 13 (68%) of the 19 cases: EWS-CHN in nine cases, TAF2N-CHN in three, and TFG-TCH in one. There were six fusion-negative cases. Signal characteristics on T1-weighted and T2-weighted MR images were non-specific with regard to each cytogenetic variant. Peripheral enhancement was seen more frequently in tumors with the EWS-CHN variant than in those with other cytogenetic variants. The characteristic pattern of enhancement corresponded to the presence of fibrous septa and peripheral areas of high cellularity within lobules, by correlation with pathologic findings. All cases with TAF2N-CHN or TFG-TCH variants showed invasion of extracompartmental structure, bone, or vessels. CONCLUSION: Extraskeletal myxoid chondrosarcoma is an uncommon soft-tissue malignancy that may be recognized by MRI features of multi-lobular soft-tissue mass often invading extracompartmental, bony, and vascular structures.

参考中文摘要：

目的：描述MRI特点外粘液样软骨肉瘤的临床病理比较结果。设计与患者：本研究包括12个男性和7名女性受试者，平均年龄为53岁（范围16-76岁）。 MRI表现，评价两种放射与协商一致意见，比较了病理组织学特征。结果：肿瘤大小不等二点〇厘米20.0厘米（平均八点九厘米）。融合基因可检测13个（ 68 ％）的19例：早期预警系统， CHN在9起案件， TAF2N - CHN三个，和过渡政府，血脂中的一个。有六个融合阴性。信号特征在T1加权和T2加权磁共振图像非特异性关于每个细胞变异。边缘强化，看到更经常肿瘤与预警系统， CHN变比那些与其他细胞遗传学变种。模式的特点加强相应的存在纤维间隔及周边地区的小叶细胞内，由相关的病理结果。所有病例与TAF2N - CHN或过渡政府，血脂变种表明入侵extracompartmental结构，骨骼，或船只。结论：外粘液样软骨肉瘤是一种罕见的软组织恶性肿瘤的可能是公认的MRI表现多小叶软组织肿块往往入侵extracompartmental ，骨和血管的结构。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

INTRODUCTION: Experimental models of osteoporosis in rabbits are useful to investigate anabolic agents because this animal has a fast bone turnover with predominant remodelling over the modelling processes. For that purpose, it is necessary to characterize the densitometric values of each type of bony tissue. OBJECTIVE: To determine areal bone mass measurement in the spine and in trabecular, cortical and subchondral bone of the knee in healthy and osteoporotic rabbits. DESIGN: Bone mineral content and bone mineral density were measured in lumbar spine, global knee, and subchondral and cortical bone of the knee with dual energy X-ray absorptiometry using a Hologic QDR-1000/W densitometer in 29 skeletally mature female healthy New Zealand rabbits. Ten rabbits underwent triplicate scans for evaluation of the effect of repositioning. Osteoporosis was experimentally induced in 15 rabbits by bilateral ovariectomy and postoperative corticosteroid treatment for 4 weeks. Identical dual energy X-ray absorptiometry (DXA) studies were performed thereafter. RESULTS: Mean values of bone mineral content at the lumbar spine, global knee, subchondral bone and cortical tibial metaphysis were: 1934+/-217 mg, 878+/-83 mg, 149+/-14 mg and 29+/-7.0 mg, respectively. The mean values of bone mineral density at the same regions were: 298+/-24 mg/cm(2), 455+/-32 mg/cm(2), 617+/-60 mg/cm(2) and 678+/-163 mg/cm(2), respectively. Bone mineral content and bone density of healthy rabbits followed a normal distribution at the four skeletal regions studied. Precision after triplicate repositioning yielded a coefficient of variation ranging from 2.6% to 3.8%. The least significant change ranged between 7.3% and 10.7%. Bone mineral density measured at the four different skeletal regions correlated significantly. Bone mineral density in osteoporotic rabbits was significantly lower in the four regions studied than that in controls, rendering a T-score of, respectively, -2.0+/-1.1 in the lumbar spine, -2.2+/-2.1 in the global knee, -1.9+/-0.6 in the subchondral bone, and -5.7+/-3.1 in the cortical tibia (P<0.05). CONCLUSIONS: DXA is a reliable and precise method to evaluate the bone mass in rabbits. Our results also suggest that subchondral bone is a bone of mixed densitometric characteristics with marked cortical bone predominance.

参考中文摘要：

导言：骨质疏松症实验模型的影响是有益的探讨蛋白同化制剂，因为这种动物有一个快速的骨转换为主改建的建模过程。为此，有必要特点的密度值的每种类型的骨组织。目的：确定区域骨密度测量脊柱和骨小梁，皮质和软骨的膝盖健康和骨质疏松的影响。设计：骨矿含量和骨密度测定腰椎，全球膝，软骨和皮质骨膝关节双能X线骨密度使用Hologic的QDR - 1000 / W型密度计29 skeletally成熟女性健康新西兰兔。 10只接受三份扫描的效果评价定位。实验性骨质疏松症的15个双边去势兔及术后糖皮质激素治疗4周。相同的双能X线骨密度（法）的研究进行了其后。结果：平均价值的骨矿含量的腰椎，全球膝盖软骨和皮质骨干骺端是： 1934 + / -217毫克， 878 + / -83毫克， 149 + / -14毫克和29 + / -7.0毫克分别。平均值骨密度在同一地区是： 298 + / -24毫克/厘米（ 2 ）， 455 + / -32毫克/厘米（ 2 ）， 617 + / -60毫克/厘米（ 2 ）和678 + / -163毫克/厘米（ 2 ）。骨矿含量和骨密度的健康兔遵循正态分布在四个骨骼肌地区研究。后三份精密定位产生了变异系数从2.6 ％至3.8 ％。最显着的变化介于7.3 ％和10.7 ％。骨密度测量在四个不同的骨骼地区显着相关。骨密度骨质疏松性显着降低家兔的四个区域研究比控制，使一个T -评分分别-2.0 + / -1.1在腰椎， -2.2 + / -2.1全球膝盖， -1.9 + / -0.6中的软骨，并-5.7 + / -3.1在胫骨皮质（ P “ 0.05 ）。结论：法是一种可靠的和精确的方法来评估骨量的影响。 Our results also suggest that subchondral bone is a bone of mixed densitometric characteristics with marked cortical bone predominance.

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

A 53-year-old man presented with a 12-year history of a progressively growing solid mass at his left shoulder. A 39x30x18-cm and 14.440-kg mass including the scapula was resected. Pathologic features were specific for chondroblastoma. During the 36-month follow-up, he had multiple inoperable metastatic lesions in his lungs. Histology of the transthoracic needle biopsy showed the metastatic nodules had features specific for chondroblastoma; however, the microscopic features additionally had hyperchromasia and increased mitotic activity in some areas. In the English literature, there are a few cases of chondroblastoma located in the scapula. It is exceptional to see this lesion in the sixth decade of life and with pulmonary metastases.

参考中文摘要：

一名53岁男子提出一个12年的历史中，逐步成长坚实的群众在他的左肩。阿39x30x18厘米和14.440千克的质量，包括肩胛骨切除。病理特点是具体的软骨母细胞瘤。在36个月的后续行动，他曾多次操作转移灶在他的肺部。组织学研究显示，经穿刺活检的转移结节了具体的软骨母细胞瘤的特点，但是，微观特征另外增加了hyperchromasia和有丝分裂活动在一些地区。在英文文献，有一些案件的软骨母细胞瘤位于肩胛骨。这是例外地看到这一病变在第六十年的生活和肺转移。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

Chondroblastoma is a rare benign bone tumor typically located in the epiphysis. We describe the first case of chondroblastoma arising in the diaphysis of a long bone. The patient was a 13-year-old girl who presented with pain over her right thigh. Radiographs showed a lytic lesion in the diaphysis of her right femur. A core biopsy and a subsequent surgical resection were performed.

参考中文摘要：

软骨母细胞瘤是一种罕见的良性骨肿瘤通常位于骨骺。我们描述了第一例软骨母细胞瘤中产生骨干的长骨。该病人是一位13岁的女孩谁提出疼痛她的右大腿。 X光片显示，溶解病变的骨干，她右股骨。一个核心活检和随后进行了手术切除。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

A case of soft tissue recurrence of chondroblastoma after attempted en bloc excision and endoprosthetic replacement is described. This tumor in the proximal humerus recurred after initial curettage and was subsequently treated by attempted en bloc excision with positive microscopic margins. The patient then presented with a large soft tissue recurrence surrounding the endoprosthesis. This periprosthetic recurrence necessitated re-excision and revision of the endoprosthesis. Recurrence is not uncommon following curettage of chondroblastoma. However, less is known about soft tissue recurrence after en bloc resection of this tumor with positive margins. A subset of chondroblastoma may exist with more locally aggressive behavior.

参考中文摘要：

1例软组织软骨母细胞瘤复发后试图整块切除及endoprosthetic更换描述。这种肿瘤在肱骨近端复发后初步刮后来试图治疗整块切除积极微观利润率。病人然后提出一个大的软组织周围的术复发。这周围复发不得不再次切除和修订术。复发的情况并不少见以下刮除软骨母细胞瘤。但是，只有了解软组织术后复发的整块切除这个肿瘤积极利润率。软骨母细胞瘤的一个子集可能存在更多的本地攻击行为。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

在详细信息中查看

摘要：

A 61-year-old woman complained of a subcutaneous mass in her right knee. MR images revealed a well-defined subcutaneous mass in the prepatellar region, containing some fluid and foci of short T2. The lesion showed some marginal contrast uptake after an administration of meglumine gadopentetate (Gd-DTPA), consistent with prepatellar bursitis. The pathological specimen, however, revealed subcutaneous sarcoidosis involving the bursa.

参考中文摘要：

一名61岁女子抱怨皮下肿块，她的右膝盖。磁共振成像显示一个明确的皮下肿块prepatellar地区，其中载有一些液体和灶短期时刻。病灶显示，摄取一些边缘对比后管理葡胺gadopentetate （磁显葡胺），符合prepatellar滑囊炎。病理标本，但是，发现皮下结节涉及囊。

出处：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘 要：

参考中文摘要：

出 处：

相关链接：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘 要：

参考中文摘要：

出 处：

相关链接：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘 要：

参考中文摘要：

出 处：

相关链接：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘 要：

参考中文摘要：

出 处：

相关链接：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘 要：

参考中文摘要：

出 处：

相关链接：

中文提供：

测试求助：

绿色通道：

参考中文标题：

PMID及链接：

全文链接：

摘要：

出处：

摘要：

出处：

摘要：

出处：

摘要：

出处：

摘要：

出处：

摘要：

出处：

摘要：

出处：

摘要：