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  1

参考中文标题:

应用免疫组织化学在诊断骨肿瘤及瘤样病变。 [修改] [ 65参]

作者单位:

Department of Pathology, Albert Einstein College of Medicine Long Island Jewish Medical Center, 270-05 76th Avenue, New Hyde Park, New York, NY, 11040, USA.

PMID及链接:

16189715 http://www.syyxw.com/Archive/Detail/16189715

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摘  要:

Immunohistochemistry (IHC) plays an important role in the diagnosis of some bone tumors, especially in the differential diagnosis of primary from metastatic non-osseous tumors and in the categorization of small-round-blue-cell tumors. This article reviews immunomarkers used in bone tumors and their diagnostic significance. [References: 65]

参考中文摘要:

免疫组织化学(免疫组)中发挥着重要作用的一些诊断骨肿瘤,尤其是在鉴别诊断主要来自转移性非骨肿瘤分类中的小轮蓝细胞瘤。本文综述immunomarkers用于骨肿瘤及其诊断意义。 [参考文献: 65 ]

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :755-70

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  2

参考中文标题:

经入侵骨肿瘤在骶髂关节。

作者单位:

Department of Medical Imaging, Mount Sinai Hospital and the University Health Network, University of Toronto, Toronto, Canada. chhaya@uthscsa.edu

PMID及链接:

16184397 http://www.syyxw.com/Archive/Detail/16184397

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摘  要:

PURPOSE: The purpose of this study was to evaluate the pattern of tumour spread across the SI articulation, correlating with cadaveric anatomic observations, in order to better understand the local spread of tumour and to assist in the assessment of local staging. MATERIAL AND METHODS: Twenty-four consecutive patients (14 male, 10 female; age range 22-89 years, mean 52 years) with primary bone tumours of the iliac bone or sacrum abutting the SI joint, in whom surgical resection of the SI joint was performed, were studied following institutional ethics approval. In all patients, preoperative magnetic resonance (MR) imaging studies of the pelvis and SI joint were reviewed for imaging evidence of transarticular extension across the SI joint. Gross pathologic and histologic assessment of possible transarticular SI joint tumour extension was performed in all patients. Nine cadaveric pelvic specimens without pelvic neoplastic disease (4 male, 5 female; age range 20-84 years, mean 59 years, median 58 years) were anatomically dissected and the articular anatomy of the SI joint examined macroscopically. RESULTS: Twelve of the twenty-four patients demonstrated imaging and histological evidence of transarticular SI joint invasion. Eight tumours infiltrated only the interosseous ligamentous aspect of the SI joint. In the remaining four cases, extensive tumour infiltrated both the cartilaginous and ligamentous aspects of the joint. No case showed tumour involvement isolated to the cartilaginous aspect of the joint. Among the cadaveric specimens studied, degenerative changes were found involving the majority of cases (6/9), with cartilage thinning and fibrillation and antero-superior marginal osteophytes seen involving the cartilaginous portion of the SI joint articulation. Four of the nine specimens demonstrated central ossification bridging the iliac and sacral aspects of the ligamentous (interosseous) SI joint. CONCLUSION: Tumour invasion across the SI articulation favours its interosseous ligamentous portion. Factors influencing transarticular tumour extension and its preferential course across the interosseous component of the articulation have been discussed. It is particularly important to assess the interosseous ligamentous portion of the SI articulation when locally staging primary pelvic bone tumours subjacent to the SI articulation, as this will have a significant impact on planning surgical management.

参考中文摘要:

目的:本研究的目的是评估模式的肿瘤遍布司衔接,与相关的解剖尸体的意见,以便更好地了解当地的传播肿瘤,并协助评估当地的分期。材料与方法: 24名病人( 14男, 10女,年龄范围22-89岁,平均52岁)与原发性骨肿瘤的髂骨或骶骨毗邻司联合,在他们手术切除的司联合进行,研究了以下制度伦理批准。所有患者,术前磁共振(先生)成像研究骨盆和SI联合成像审查证据经延长整个司联合。病理组织学总值和评估可能经司联合肿瘤扩展是在所有患者。 9尸体骨盆标本没有骨盆肿瘤疾病( 4男5女,年龄范围20-84岁,平均59岁,中位数58岁)被解剖解剖关节解剖宏观司联合审查。结果: 12名24例,影像和病理证据经司联合入侵。肿瘤浸润8只间韧带方面的司联合。在其余4起案件中,广泛肿瘤浸润的软骨和韧带方面的联合。任何情况下,显示肿瘤参与的软骨分离方面的联合。在标本的研究,发现了退行性变化,涉及大多数情况下( 6 / 9 ) ,软骨变薄和颤动和安特罗-优于边际osteophytes看到涉及软骨部分司联合衔接。四个9标本表明中央骨化弥合和骶髂方面的韧带(间)司联合。结论:肿瘤浸润整个司衔接赞成间韧带部分。经肿瘤的影响因素及其延长优惠整个过程的组成部分间的衔接问题进行了讨论。尤其重要的是,评估间韧带部分司时,当地分期衔接小学骨盆骨肿瘤下方的司衔接,因为这将有重大影响的规划外科管理。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :771-7

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  3

参考中文标题:

豆状核变性的发育不良髋关节。计算机断层扫描研究。

作者单位:

Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark. sjac@dadlnet.dk

PMID及链接:

16211385 http://www.syyxw.com/Archive/Detail/16211385

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摘  要:

BACKGROUND: Hip dysplasia is considered pre-osteoarthritic, causing degeneration in young individuals. OBJECTIVE: To determine the pattern of degenerative change in moderate to severely dysplastic hips in young patients. DESIGN AND PATIENTS: One hundred and ninety-three consecutively-referred younger patients with hip pain believed to be caused by hip dysplasia constituted the study cohort. The average age was 35.5 years (range, 15-61 years). They were examined by close-cut transverse pelvic and knee computed tomography and antero-posterior radiographs (CT). We identified 197 hips with moderate to severe dysplasia, and 78 hips with normal morphology in the study cohort, whilst 111 hip joints were borderline dysplastic according to preset definitions. Comparative analyses of anatomy and distribution of degeneration between dysplastic and normal hips in the study cohort were performed. RESULTS: In dysplastic hips the anterior acetabular sector angle was significantly and inversely associated to femoral anteversion (p < 0.001). The center-edge (CE) angle, the acetabular angle (AA), and the acetabular depth ratio (ADR) were significantly interrelated (p < 0.001; correlation coefficients ranging from -0.8 to 0.7). Fifty-one hips were subluxated (24R/27L). There were no cases of complete dislocation. The formation of subchondral cysts or osteophytes in dysplastic hips was significantly associated with reduced minimum joint space width (p ranging from 0.005 to 0.02). However, in 67 hips with acetabular cysts, only 6 hips had minimum joint space widths = 2.0 mm (8.9%) in the coronal plane. In 96 cases with acetabular cysts found in the sagittal plane, 43 cases had minimum joint space widths = 2.0 mm (44.7%). Bony rim detachment at the site of labral insertion was recorded in 30 hips. Twenty-three of these were dysplastic (p = 0.01). CONCLUSIONS: Degeneration was most often found in the anterolateral part of the dysplastic hip joints. Most cysts were located above the transition zone between the bony and the fibrocartilaginous acetabulum, and we found a significantly- increased number of cases with avulsed bony fragments at the antero-lateral labral insertion in dysplastic hips compared to normal hips. It seems likely that the early degenerative process in dysplastic hips originates at the watershed zone between the acetabular labrum and the acetabular cartilage in response to subluxation and femoroacetabular impingement.

参考中文摘要:

背景:髋关节发育不良被认为是前骨性关节炎,造成变性青年个人。目的:确定的格局退行性改变,中度至严重的发育不良髋年轻患者。设计与患者: 106 93连续-提到年轻患者髋关节疼痛认为是造成髋关节发育不良的研究队列组成。平均年龄35.5岁(范围15-61岁) 。他们进行了密切切横向骨盆和膝盖计算机断层扫描和安特罗,后X光片(电脑断层) 。我们确定了197臀部与中度至重度异型增生, 78髋关节的正常形态的研究队列,同时有111个髋关节发育不良据交界预置定义。对比分析解剖和分配之间变性和正常髋关节发育不良的研究队列进行。结果:在发育不良髋臼部门前角显着负相关,并以股骨前倾( p “ 0.001 ) 。该中心边缘( CE认证)的角度,髋臼角(机管局)和髋臼深度比美国存托凭证( ADR )有显着关联( p “ 0.001 ;相关系数为-0.8至0.7 ) 。 51个髋半脱位( 24R/27L ) 。目前还没有完整的情况下脱位。形成软骨囊肿或发育不良髋osteophytes在显着减少相关的最低关节间隙宽度( p范围从0.005到0.02 ) 。然而,在67个髋关节囊与髋臼中,只有6髋关节间隙已最低宽度= 2.0毫米( 8.9 % )在冠状面。在96例髋臼囊肿发现的矢状面, 43例关节间隙最小宽度= 2.0毫米( 44.7 % ) 。骨环支队在现场的labral插入录得30臀部。有23个,这些人不典型增生( P值0.01 ) 。结论:豆状核变性是最常见的前一部分,髋关节发育不良。囊肿位于最上方的过渡区之间的骨和fibrocartilaginous臼,我们找到了一个显着,越来越多的情况下与撕脱骨碎片在安特罗外侧labral插入增生臀部比较正常臀部。看起来似乎早期退行性进程发育不良髋源于在分水岭区之间的髋臼唇和髋臼软骨响应半脱位和femoroacetabular冲击。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :778-84

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  4

参考中文标题:

外间叶性软骨肉瘤:一个成像审查的10个新患者。

作者单位:

Department of Orthopedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Disease, 1-3-3 Nakamichi, Higashinari-ku, Osaka, 567-8511, Japan. hashinob-ouh@umin.ac.jp

PMID及链接:

16211384 http://www.syyxw.com/Archive/Detail/16211384

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摘  要:

OBJECTIVE: Extraskeletal mesenchymal chondrosarcoma (EMC) is a rare soft-tissue tumor that most arises in young adults. Because of its rarity, few imaging studies have been reported to date. The purpose of this study was to elucidate the imaging features of this tumor. DESIGN: We conducted a multi-institutional study in cooperation with five referral cancer centers in Japan. Imaging findings of ten new EMC cases, including conventional radiography, computed tomography (CT), and magnetic resonance imaging (MRI), performed at each institute, were reviewed along with clinical features. PATIENTS: Ten patients with EMC, who had been treated at each hospital from 1990 to 2001, participated in this study. RESULTS AND CONCLUSIONS: Soft-tissue masses with well-demarcated, dense and granular calcification were most frequently observed on plain radiographs and CT scans. T2-weighted MR images most clearly depicted a two-component structure composed of calcified and uncalcified areas, and enhanced MRI showed inhomogeneous enhancement in both areas. Although the sensitivity and specificity of these findings are unknown, they might be characteristic and have diagnostic value for this rare tumor.

参考中文摘要:

目的:外间叶性软骨肉瘤(电磁兼容)是一种罕见的软组织肿瘤,大部分发生在年轻的成年人。由于其稀有性,很少成像研究已经报告。本研究的目的是要阐明的影像学特征的肿瘤。设计:我们进行了多机构合作研究5转诊癌症中心在日本。影像学表现的10个新EMC的情况下,包括常规X线摄影,计算机断层扫描( CT )和磁共振成像( MRI ) ,表现在每一个研究所,进行了审查与临床特点。患者: 10例与EMC ,谁处理过的每个医院1990年至2001年参加了这项研究。结果和结论:软组织群众界限分明,高密度和颗粒钙化最常观察到X线和CT扫描。 T2加权MR图像最清楚的描述了一个双组分的结构组成的钙化和uncalcified领域,增强MRI显示不均匀加强在这两个领域。虽然敏感性和特异性,这些调查结果是未知的,他们可能会特点和诊断价值这一罕见的肿瘤。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :785-92

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  5

参考中文标题:

Cherubism与第一型神经纤维瘤病,多溶骨性病变的两个股骨:以前undescribed协会的调查结果。

作者单位:

Departamento de Anatomia Patologica, Hospital Universitario "12 de Octubre", Carretera de Andalucia Km. 5400, 28041, Madrid, Spain. fmartinez.hdoc@salud.madrid.org

PMID及链接:

16096755 http://www.syyxw.com/Archive/Detail/16096755

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摘  要:

We present a patient with neurofibromatosis type 1, with the clinical, radiological and histological features of cherubism mandibular lesions, and multiple osteolytic, geographic lesions in both femurs, consistent with multiple non-ossifying fibromas. We have been unable to find a similar case in the world literature. We discuss our findings in relationship with a number of syndromes that present clinical, radiological or pathological similarities.

参考中文摘要:

我们提出一个病人,第一型神经纤维瘤病,临床,放射学和组织学特征cherubism颌骨病变,以及多个溶骨,地理病变在股骨,符合多个非骨化性纤维瘤。我们一直无法找到一个类似的情况在世界文学。我们讨论我们的调查结果与一些临床症状,目前,放射性或病理相似之处。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :793-8

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  6

参考中文标题:

小儿lipofibromatosis上肢。

作者单位:

Department of Diagnostic Imaging, KK Women's and Children's Hospital, 100 Bukit Timah Road, 229899, Singapore, Singapore.

PMID及链接:

16096756 http://www.syyxw.com/Archive/Detail/16096756

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摘  要:

The imaging features of extensive lipofibromatosis presenting in a 1-day-old female infant are reported. This lesion involved her entire right upper limb, extending from the axilla to the palm of the hand. Radiographs showed marked deformity and thinning of all the right upper-limb bones due to pressure effect of soft-tissue enlargement, especially affecting the distal humerus and proximal forearm bones. Magnetic resonance imaging showed a huge soft-tissue mass infiltrating most of the muscles of the entire upper limb, with bony erosion. The mass was largely T1-isointense, moderately T2-hyperintense and showed marked enhancement. There were intra-lesional signal changes consistent with fatty elements. A lesion debulking procedure was performed and the histology was that of lipofibromatosis. The limb was found to be non-viable after the procedure and a subsequent above-elbow amputation was performed. Although the resection margins were not clear, she had no further recurrence over a subsequent 3-year follow-up period.

参考中文摘要:

的影像学特征广泛lipofibromatosis提出了1天的女婴报告。这种病变涉及她的整个右上肢,扩大从腋下到手掌。 X光片明显畸形和变薄的所有权利上肢骨骼由于压力作用的软组织的扩大,特别是影响肱骨远端和近端前臂骨头。磁共振成像显示了巨大软组织肿块浸润大部分肌肉整个上肢,与骨侵蚀。大众主要是T1的isointense ,适度的T2 -高和显着增强。有内部病灶信号变化符合脂肪酸组成部分。甲病变减的程序进行和组织学的是lipofibromatosis 。肢体被发现非可行后的程序和随后的上述肘部截肢手术。虽然切缘不很清楚,她没有再次发生了后来的3年随访期间。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :799-802

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  7

参考中文标题:

Tophaceous痛风颈椎。

作者单位:

Department of Orthopaedic Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia, 5000.

PMID及链接:

16028084 http://www.syyxw.com/Archive/Detail/16028084

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摘  要:

Gout is a common metabolic disorder typically affecting the distal joints of the appendicular skeleton. Involvement of the axial skeleton, particularly the facet joints and posterior column of the cervical spine, is rare. This case report highlights such a presentation in a 76-year old female who presented with cervical spine pain following a fall. Her radiological findings were suggestive of a destructive metastatic process. Histological diagnosis confirmed tophaceous gout.

参考中文摘要:

痛风是一种常见的代谢紊乱通常影响远端关节的阑尾骨架。参与轴向骨架,特别是小关节和后柱颈椎,是罕见的。这种情况下这样的报告着重介绍了76岁的女性谁提出以下颈椎疼痛下降。她放射性调查结果暗示具有破坏性转移的进程。病理诊断证实tophaceous痛风。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :803-6

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  8

参考中文标题:

葡萄糖- PET显像对慢性肾盂血肿扩大与大规模骨破坏。

作者单位:

Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. hamada@tracer.med.osaka-u.ac.jp

PMID及链接:

15834566 http://www.syyxw.com/Archive/Detail/15834566

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摘  要:

Chronic expanding hematoma is a rare presentation of a hematoma characterized by a persistent increase in size for more than a month after the initial hemorrhage. We present a 65-year-old man with a chronic expanding hematoma in his ilium who was receiving anticoagulant treatment. The patient had a delayed manifestation of a femoral neuropathy with massive bone destruction. 2-Deoxy-[18F]fluoro-D: -glucose (FDG) positron emission tomography (PET) imaging revealed an increased uptake in the rim of the mass in images acquired 1 h after FDG injection. FDG-PET scans were performed using a dedicated PET scanner (HeadtomeV/SET2400 W, Shimadzu, Kyoto, Japan), and the PET data for the most metabolically active region of interest (ROI) were analyzed. The maximum standardized uptake value (SUVmax) was set to a cut-off point of 3.0 to distinguish between benign and malignant lesions. The SUVmax of the patient's lesion was 3.10, suggesting a malignant lesion. The characteristics of FDG-PET images of chronic expanding hematomas, including the uptake of FDG in the peripheral rim of the mass as a result of inflammation, should be recognized as a potential interpretive pitfall in mimicking a sarcoma.

参考中文摘要:

慢性扩展血肿是一种罕见的介绍血肿特点是持续增加,规模超过一个月后的出血。我们提出一个65岁的男子与慢性扩展血肿谁在他的髂骨接受抗凝治疗。病人没有及时反映了大量的股神经病变与骨破坏。 2 -脱氧- [ 18 ]氟- D组:葡萄糖(葡萄糖)正电子发射断层扫描技术( PET )图像显示,增加摄取的边缘图像中的大规模收购后1 h葡萄糖注射液。葡萄糖- PET扫描进行使用专用聚酯扫描器( HeadtomeV/SET2400钨岛津,日本京都) ,和宠物数据代谢最活跃的感兴趣区域( ROI )进行了分析。最大标准摄取值( SUVmax )被设置为一个分界点的3.0区分良,恶性病变。该SUVmax患者的病灶是3月10日,提出了恶性病变。的特点,葡萄糖, PET图像慢性血肿扩大,包括吸收的葡萄糖周边环大众由于炎症,应该认识到作为一个潜在的阐释陷阱模仿肉瘤。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :807-11

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参考中文标题:

剥脱性骨软骨炎后髋臼旋转截骨术髋关节发育不良。

作者单位:

Department of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku 113-8421, Tokyo, Japan. nozawa@med.juntendo.ac.jp

PMID及链接:

15782341 http://www.syyxw.com/Archive/Detail/15782341

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摘  要:

We encountered a rare case of osteochondritis dissecans of the femoral head after rotational acetabular osteotomy that recovered with conservative treatment 4 years after the detection of characteristic radiological findings.

参考中文摘要:

我们遇到了一例罕见的剥脱性骨软骨炎股骨头髋臼旋转截骨后的恢复与保守治疗4年后的特征放射性检测结果。

出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :812-5

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  10

参考中文标题:

椎体后根性疼痛:和预防并发症。[意见]。

作者单位:

PMID及链接:

16215706 http://www.syyxw.com/Archive/Detail/16215706

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出  处:

Skeletal radiology. 2005 Dec  ,34 (12) :816

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